In March 2000, Strategy executive chairman Michael Saylor watched more than $6 billion disappear from his fortune in a single day.MicroStrategy’s shares had plummeted more than 60%, thrusting the thirty-five year old software entrepreneur into the center of the dot-com crash. The company later settled civil fraud charges with the US Securities and Exchange Commission over its accounting practices without admitting or denying wrongdoing. MicroStrategy did not cause the dot-com bubble to burst, but the saga was one of the era’s high-profile corporate blowups and the company became a symbol of the periods excesses and risks. Now, more than 25…

The age-adjusted cancer mortality rate in the United States continues to fall. The decrease is largely the result of a combination of the continuing decline in smoking, the development of earlier detection diagnostics, and ever more effective treatments. Cancer Statistics, 2026 The experience of former Sen. Ben Sasse (R–Neb.) is an example of the development of more effective treatments. In December, Sasse was diagnosed with Stage 4 pancreatic cancer and given just a few months to live. His continuing survival can likely be chalked up to participating in a clinical trial of the new anti-cancer drug daraxonrasib that targets a…

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